Support for financing COVID-19 drugs

Question écrite de M. Pascal ARIMONT - Commission européenne

Question de M. Pascal ARIMONT,

Diffusée le 19 avril 2021

Subject: Support for financing COVID-19 drugs

According to media reports, the Technical University of Braunschweig and a biotechnology firm have developed an antibody drug (antibody therapy) against coronavirus which would be used particularly to treat hospitalised patients with moderate to serious COVID-191. Clinical studies are said to have shown the drug to be highly effective, and it is set to undergo further trials in test centres in Germany and elsewhere in Europe. But researchers and the firm involved are short of funds, with press reports saying they need another EUR 50 million. Experts are calling for more support for the development of antibody drugs as well as vaccines.

1. What is the Commission’s strategy for the rapid development of drugs to treat coronavirus?

2. Is the Commission currently supporting similar research projects aimed at developing drugs – apart from vaccines – against coronavirus?

1 https://www.zdf.de/nachrichten/video/corona-medikament-ohne-finanzierung-100.html –

https://www.ndr.de/ratgeber/gesundheit/Antikoerper-Therapie-gegen-Corona-Welche-Medikamente-gibt- es,coronavirus4280.html

Réponse - Commission européenne

Diffusée le 12 juillet 2021

Answer given by Ms Gabriel on behalf of the European Commission

(13 July 2021)

The Commission has been at the forefront of funding research and innovation and coordinating European and global research efforts in the fight against COVID-19 (2).

Since January 2020, the Commission has mobilised over EUR 800 million through several special actions addressing, among others, the development of vaccines (3) and new treatments for COVID-19 (4). An EU strategy on COVID-19 therapeutics including future actions has recently been published (5).

This strategy mentions that some of these projects are already delivering results including the identification of existing medicines (6) to be used as therapeutics and novel antigen-based therapies (7), and it announced its first emergency funding under Horizon Europe for urgent research into coronavirus variants (8).

In addition, the Commission is currently funding two projects, RECOVER (9) and EU-RESPONSE (10) that include large-scale, EU-wide clinical trials on therapeutics for COVID-19. These are REMAP-CAP for COVID-19 (11), DisCoVeRy and EU-SOLIDACT.

A trial coordination board with a joint access advisory mechanism, a single entry point for developers with new, to be tested compounds has been established (12).

These trials have already delivered important knowledge improving the outcome of COVID-19 patients. For example, the REMAP- CAP trial found that Tocilizumab and Sarilumab could cut the relative risk of death of severely-ill COVID-19 patients by 24% (13).

Support for small and medium-sized enteprises is also provided via the European Innovation Council Accelerator, which already provides support to 36 projects aimed at tackling COVID-19 of which 22 concern development of treatments for COVID-19. For example, the BRIGHT project has developed an antibody-based treatment that is now in clinical development (14).

⋅1∙ https://www.zdf.de/nachrichten/video/corona-medikament-ohne-finanzierung-100.html — https://www.ndr.de/ratgeber/gesundheit/Antikoerper-Therapie-gegen-

Corona-Welche-Medikamente-gibt-es,coronavirus4280.html

⋅2∙ https://ec.europa.eu/info/research-and-innovation/research-area/health-research-and-innovation/coronavirus-research-and-innovation_en

⋅3∙ https://ec.europa.eu/info/research-and-innovation/research-area/health-research-and-innovation/coronavirus-research-and-innovation/vaccines_en

⋅4∙ https://ec.europa.eu/info/research-and-innovation/research-area/health-research-and-innovation/coronavirus-research-and-innovation/treatments_en ;

https://op.europa.eu/en/web/eu-law-and-publications/publication-detail/-/publication/e6a26152-c4dd-11eb-a925-01aa75ed71a1 ⋅5∙ https://ec.europa.eu/info/sites/default/files/communication-eu-strategy-covid-19-therapeutics_en.pdf ;

https://ec.europa.eu/commission/presscorner/detail/en/ip_21_2201

⋅6∙ https://digital-strategy.ec.europa.eu/en/news/coronavirus-eu-funded-project-launches-clinical-trial-coronavirus-treatment-italy

⋅7∙ https://ec.europa.eu/info/news/eu-funded-researchers-develop-potential-new-treatment-against-sars-cov-2-2021-mar-25_en

⋅8∙ https://ec.europa.eu/commission/presscorner/detail/en/IP_21_1548 ; https://ec.europa.eu/info/news/eu-invest-eu150-million-research-counter-coronavirus-

variants-2021-feb-17_en

⋅9∙ https://www.recover-europe.eu/

⋅10∙ https://eu-response.eu/

⋅11∙ https://www.remapcap.eu/ ; https://www.remapcap.org/coronavirus

⋅12∙ [email protected]

⋅13∙ https://www.imperial.ac.uk/news/211514/arthritis-drugs-reduce-mortality-time-icu/ ; https://www.nejm.org/doi/full/10.1056/NEJMoa2100433

⋅14∙ https://www.businesswire.com/news/home/20210503005365/en/XENOTHERA-And-Its-Partner-Excelya-Announce-the-Recruitment-of-the-First-Patient-in-The-

EUROXAV-Clinical-Trial-of-its-COVID-Treatment-XAV-19



























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